Botox® therapy is a way to block the sweat glands to reduce severe perspiration from the armpits, the forehead, and often the hands and feet.

In 2004, the U.S. Food & Drug Administration (FDA) approved Botox® for the treatment of severe primary axillary hyperhidrosis (excessive sweating of the underarms) in patients unable to obtain relief using topical antiperspirants.

When used to treat underarm excessive sweating, Botox® has been shown to result in an 82-87% decrease in sweating. Results start to be noticeable approximately 2 to 4 days after treatment with the full effects usually noted within 2 weeks. Dryness typically lasts 6 to 12 months but some studies have found it can last as long as 14 months. Compensatory sweating (sweating on other body parts) has not been found to be a concern.

Botox® can also be used for excessive sweating of hands, feet, foreheads and under the breast areas. Follow-up injections are required to maintain dryness. These repeat injections may be necessary at intervals varying from 6 to 12 months depending on the treated area.